He mea kākau kūʻokoʻa ʻo Mark Gurarie, mea hoʻoponopono a me ke aʻo hapa manawa ma ke kākau ʻana ma ke Kulanui ʻo George Washington.
ʻO Anita Chandrasekaran, MD, Master of Public Health, i hōʻoia ʻia e ka Board of Internal Medicine and Rheumatology, i kēia manawa ke hana nei ma ke ʻano he rheumatologist ma ka Hartford Healthcare Medical Group ma Connecticut.
ʻO Gel-One (cross-linked hyaluronate) kahi koho lapaʻau no ka osteoarthritis o ke kuli (OA).He injection kēia e kōkua i ke kāohi ʻana i ka ʻeha pili.
Loaʻa ia mai ka protein (hyaluronic acid) i unuhi ʻia mai nā pū moa a i ʻole nā hui.Hana maoli ke kino o ke kanaka i kēia protein e lubricate i nā hono.ʻO kāna kuleana ka hoʻihoʻi ʻana i ka pae o kēia protein.
Ua'āpono muaʻiaʻo Gel-One e ka US Food and Drug Administration (FDA) i ka makahiki 2001. Ua loiloi waleʻia i loko o ka ho'āʻo hoʻokolohua a hōʻoia i ka maikaʻi i ka ho'ēmiʻana i nā heluʻeha a hiki i ka 13 wiki, akāʻo nā mea hopena'ē aʻe, e like me ka paʻakikī A me ke kino. hana, ʻaʻohe ʻokoʻa helu helu me ka placebo.
ʻAʻohe lāʻau lapaʻau piha no ka OA.Hana ʻia kēia lapaʻau ma hope o ka hoʻāʻo ʻana i nā ʻano hoʻokele ʻē aʻe (e like me ka lawe ʻana i ka lāʻau lapaʻau a i ʻole ka hoʻoponopono ʻana i ka nohona).
E like me nā lāʻau lapaʻau, ʻaʻohe hopena ʻaoʻao a me nā pilikia ʻo Gel-One injection.Inā loaʻa iā ʻoe ka OA, he mea nui e ʻike e pili ana i kāu hoʻolālā lapaʻau.
He kūpono ʻo Gel-One no ke kuli OA, kahi i hōʻike ʻia e ka ʻaʻahu a me ka waimaka, kahi e hōʻeha ai.ʻO ka OA ke ʻano maʻamau o ka maʻi ʻāʻī, a ʻoiai hiki ke hoʻopilikia i kekahi, ʻoi loa ia i nā poʻe ma mua o 65.
ʻO ka mea mua, inā ʻaʻole maikaʻi nā lāʻau lapaʻau ʻē aʻe (e like me ka lawe ʻana i nā lāʻau anti-inflammatory non-steroidal (NSAID) a i ʻole ka hoʻoikaika kino kino), e hoʻāʻo ʻia ʻo Gel-One.No ka mea he maʻi holomua a hiki ʻole ke hoʻihoʻi ʻia ʻo OA, ʻoiai he koho paha ke ʻoki ʻana, ʻo ka mālama ʻana ia mea ʻo ia ka mālama ʻana i nā hōʻailona.Hōʻike kēia injection i kahi lāʻau hoʻohui paʻa.
Ma mua o ka noʻonoʻo ʻana iā Gel-One injection ma ke ʻano he lapaʻau, pono ka ʻike kūpono o OA.Pehea e loiloi ai i kēia kūlana?ʻO ka haʻihaʻi wikiwiki kēia:
E kūkākūkā i nā lāʻau lapaʻau, nā mea hoʻohui, a me nā huaora āu e lawe nei me kāu mea mālama ola.ʻOiai ke kau nei kekahi mau lāʻau lapaʻau i kahi pilikia liʻiliʻi o ka launa pū ʻana, hiki i nā lāʻau lapaʻau ʻē aʻe ke hōʻole loa a i ʻole e noʻonoʻo pono inā ʻoi aku ka maikaʻi a me nā pōʻino o ka mālama ʻana ma mua o kāu hihia.
ʻO nā huahana hyaluronic acid i kūʻai ʻia ma lalo o nā inoa e like me Restylane, Juvéderm a me Perlane he mau mea hoʻopiha maka i hoʻohana ʻia e hoʻomaʻemaʻe i nā wrinkles a i ʻole nā lehelehe plump.E like me nā hui, e emi ana nā pae hyaluronic acid me ka makahiki, e alakaʻi ana i ka ʻili ʻili.Ma ka hoʻokomo ʻana i kēia mau mea i ka maka, e ʻoi aku ka paʻa o ka ʻili.
Eia hou, hiki i nā niho niho ke hoʻohana i ka waikawa hyaluronic topical ma ke ʻano he papa hana lapaʻau no ka ʻāʻī ʻana o ka ʻāʻī.Ma waho aʻe o nā lāʻau lapaʻau ʻē aʻe, kōkua pū kekahi i ka hōʻemi ʻana i ka mumū ma kēia mau wahi a kōkua i ka mālama ʻana i ka gingivitis, periodontitis a me nā pilikia ʻē aʻe.
Hāʻawi wale ʻia nā injections Gel-One e nā mea mālama olakino ma nā wahi o ka haukapila, a e like me ka mea i ʻōlelo ʻia ma luna nei, ʻaʻole ʻōlelo ʻia e hana i kēia ʻano lapaʻau ma mua o hoʻokahi manawa i kēlā me kēia kuli.Hoʻopili ʻia i loko o kahi syringe aniani i hoʻokomo mua ʻia, hoʻopiha ʻia me 3 milliliters (mL) o ka hopena, aia ka 30 milligrams (mg) o ka hyaluronic acid.
ʻO Seigaku Corporation, ka mea nāna i hoʻopuka i ka Gel-One, a ua ʻōlelo ka FDA ʻaʻole pono e lawe i nā manawa he nui a hoʻololi paha i ka ʻōlelo kuhikuhi.Eia nō naʻe, inā ʻaʻole maopopo ʻoe, e ʻoluʻolu e kūkākūkā i ke ʻano kūpono me kāu kauka.
ʻOiai ke hilinaʻi nei ka hoʻokele a me ka mālama ʻana i kāu mea mālama ola, pono e hoʻomaopopo i ke ʻano o kēia.ʻO ka hoʻohana pono ʻana o Gel-One penei:
ʻO nā hopena ʻaoʻao maʻamau o Gel-One injection ke hoʻoholo nei;akā naʻe, pono ʻoe e hōʻike i kāu kahu mālama ola inā hoʻomau a hiki mai paha kēia mau pilikia.Aia lākou:
Ma hope o ka mālama ʻana, e ʻoluʻolu e nānā i kou manaʻo.Inā manaʻo ʻoe makemake ʻoe i ke kōkua, e ʻoluʻolu e noi i ke kōkua.
ʻO nā hopena koʻikoʻi i ka Gel-One he kakaikahi a ʻo ka hapa nui ke kumu o nā hopena maʻi i nā lāʻau lapaʻau.Inā loaʻa iā ʻoe kekahi o kēia mau kūlana, e ʻoluʻolu e ʻimi koke i ke kōkua:
ʻO ke kumu i ʻae ʻia ai ʻo Gel-One ʻo ia ka lawelawe ʻana o ka lāʻau lapaʻau e kahi mea mālama olakino, a laila e hōʻemi ana i ka manawa o ka overdose.No ka mea, ʻaʻole hāʻawi ʻia i nā manawa he nui (ma ka liʻiliʻi ma ka kuli hoʻokahi), ʻoi loa ka haʻahaʻa o ka pilina ma waena o kēia lāʻau a me nā lāʻau ʻē aʻe āu e lawe nei.
Eia nō naʻe, he mea nui inā ua hoʻomaʻemaʻe ʻia kou ʻili me kahi disinfectant ammonium quaternary, ʻaʻole pono ʻoe e loaʻa i nā injections Gel-One.Hiki i nā lāʻau lapaʻau ke hana i kēlā mau hoʻonā.
ʻO Casale M, Moffa A, Vella P, etc. Hyaluronic acid: ka wā e hiki mai ana o ka dentistry.ʻōnaehana loiloi.Int J Immunopathol Pharmacol.2016;29(4):572-582.
Ka manawa hoʻouna: ʻOkakopa-19-2021